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We would like also to pinpoint the importance that in addition to metabolomic studies, in -depth studies on biochemical pathways using a multi-omics approaches in in vitro hepatotoxicity studies, such as transcriptomics, proteomics, and metabolomics, provides a more comprehensive understanding of the effects of xenobiotics at cellular level
The human body naturally produces some L-carnitine, but factors such as aging, dietary restrictions, or high levels of physical activity can reduce its availability
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Furthermore, standardization of protocols to reduce variability, including microplastic types, sizes, and concentrations, is critical for reliable risk assessment and management strategies
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